There are a lot of differences in pathophysiology of schizophrenia than non-schizophrenia. Anatomic, neurotransmitter, and immune system abnormalities are included in schizophrenia patients.
According to Medscape website, “the ventricles are somewhat larger, there is decreased brain volume in medial temporal areas, and changes are seen in the hippocampus”. The magnetic resonance imaging studies that had been used for these patients show anatomic abnormalities in a network