Adenoid Carcinoma Research Paper

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Adenoid cystic carcinoma (ACC), formerly known as cylindroma, is an indolent but highly malignant tumor with a predisposition for recurrence. It can occur in any salivary gland but 50 – 60% develop within the minor salivary glands.Godge Its characteristic microscopic pattern is described as cribriform, with nests and columns of cells of rather bland appearance arranged concentrically around gland-like spaces (“pseudocysts”) filled with homogenous eosinophilic Periodic Acid Schiff positive material. In the female genital tract, it occurs mainly in the Bartholin’s gland and cervix.Longacre Adenoid cystic carcinoma of the ovary is uncommon. Its incidence is unknown, with only a few cases reported in the English literature.
The first case of adenoid cystic carcinoma of the ovary was described in 1995 by Eichhorn and …show more content…
Endometrioid carcinoma, whether benign, borderline, or well differentiated, may present with tubular and acinar structures exhibiting “cribriform” intraglandular bridging on light microscopy but can be differentiated through visualization of foci of squamous differentiation and marked cellular heterogeneity. Microcystic serous carcinoma may also present with a similar microscopic pattern but is distinguished through the absence of distinct ductal-type cells and myoepithelial cells with large spaces filled with basal lamina. Microfollicular granulosa cell tumor may present with similar immunohistologic findings but contain distinctive pale, oval or angulated nuclei with nuclear grooves. Carcinoid tumors may also exhibit microacinar features with eosinophilic material within the lumen. These acini, however, are typically are uniform in size and do not contain basal lamina
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