Argumentative Essay On Chemotherapy

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As a delivery capsule for toxic drugs is the common use of bacteria in modern medicine, especially in cancer treatment. Chemotherapy is the most usual way of cancer treatment. It is targeted not only for cancer cells but also all rapidly dividing cells. This contains intestinal cells, bone marrow and stomach cells, etc. Because the use of chemotherapy as cancer treatment inhibit the immune system and may cause sickness and even other cancers, site-specific delivery is so important in modern medicine. For instance, the Cancer Research UK has improved the bacterium Escherichia Coli to transport an enzyme which destroys cancer cells. Researchers genetically altered the bacterium in two ways. Firstly, a gene known as invasin was added allowing the bacteria to pass through the human cells membrane. Because the bacteria were previously unable to. Secondly, the researchers added a gene called listeriolysin O, a gene which turns the bacteria into a sort of ticking …show more content…
The proteins act to specifically target the claudin-3 and claudin-4 epithelial receptors present in breast, prostate, lung, endometrial, thyroid, and pancreatic cancer tumors. The carboxy-terminal fragment of the CPE bacteria has a high-affinity to certain cell receptors, such as claudin-3 and claudin-4 cell receptors which are heavily present in the previously listed tumors. In the future, CPE could potentially be used in two ways. For one, physicians have potential to detect residual amounts of disease by coupling radioactive isotopes to the CPE. This is a very effective way to locate minor metastasized parts of cancer throughout a patient’s body. The second method is that CPE can be used is by coupling anticancer agents to it, which CPE would deliver directly to the tumor for therapeutic
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