1964 - His parents divorce when Barack is two years old.
Late 1960s - Lives in Indonesia with mother and stepfather Lolo Soetoro.
1971 - Returns to Hawaii to live with his maternal grandparents and attend school.
November 24, 1982 - Barack Obama, Sr., dies in a car accident in Kenya.
1992-2004 - Practices civil rights law and teaches constitutional law at the University of Chicago Law School.
November 7, 1995 - His mother, Stanley Ann (Dunham) Soetoro, 52, dies of ovarian cancer in Honolulu.
1995 - Publishes his autobiography "Dreams from my Father," in which he admits to experimenting with marijuana and cocaine as a teenager.
1997 - 2005 - Illinois State Senator, representing the 13th District.
2000 - Runs for the U.S. House seat in Illinois' 1st District and loses to former Black Panther Bobby Rush.
July 27, 2004 - Delivers the keynote address at the Democratic National Convention.
November 2004 - Wins the U.S. Senate race in Illinois, defeating Alan Keyes. It is the first time in history a Senate race is between two African-American candidates.
January 4, 2005 - Is sworn in as U.S. senator.
2006 - Wins a Grammy for Best Spoken Word Album for his reading of "Dreams From My Father."
August 20 - September 3, 2006 - Tours five African countries, including a visit to Nyangoma-Kogelo, Kenya, his late father's hometown.
January 16, 2007 - Files papers with the FEC to form a presidential exploratory committee.
February 10, 2007 - Announces his candidacy for president at an event in Springfield, Illinois.
November 3, 2007 - Makes a surprise guest appearance on Saturday Night Live, as himself.
January 3, 2008 - Wins the Iowa Democratic Caucuses with 38% of the vote.
February 10, 2008 - Wins his second Grammy Award for Best Spoken Word Album for the audio version of his book, "The Audacity of Hope: Thoughts on Reclaiming the American Dream." His competition is former Presidents Bill Clinton and Jimmy Carter.
March 18, 2008 - Makes a speech in Philadelphia defending his former pastor, Rev. Jeremiah Wright, who made racially-charged and anti-government comments during sermons.
June 3, 2008 - Secures enough delegates to win the nomination - 2,118 - after the South Dakota and Montana primaries.
June 19, 2008 - Announces he will not accept federal matching funds for his presidential campaign, foregoing $80 million dollars in federal money and a cap on how much he can spend.
August 23, 2008 - Chooses Senator Joseph Biden (D-DE) as his running mate and has first rally with Biden in Springfield, Illinois in front of the old state capitol.
August 27-28, 2008 - Is officially nominated as and accepts the nomination for president on the democratic ticket, becoming the first African American candidate in U.S. history to lead a major party.
November 3, 2008 - Grandmother, Madelyn Dunham, 86, dies in Hawaii after a long battle with cancer.
November 4, 2008 - Is elected president of the United States with an estimated 66.7 million popular votes and 365 electoral votes.
November 16, 2008 - Resigns his seat in the U.S. Senate.
December 17, 2008 - Is named Time Magazine's "Person of the Year."
January 20, 2009 - Is sworn in as the 44th president of the United States
January 22, 2009 - Issues executive orders regarding the closing of Guantanamo Bay, torture and creating a review of detention facilities and of individual cases.
April 6, 2009 - During a speech made in Turkey, is quoted as saying, "The United States is not, and will never be, at war with Islam."
April 7, 2009 - Makes a surprise trip to Iraq, his first as president.
October 9, 2009 - Is awarded the Nobel Peace Prize.
March 23, 2010 - Signs the health care reform bill into law.