Hyperlipidemia Research Paper

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Hyperlipidemia, especially low density lipoprotein is associated with cardiovascular risk. Lipid lowering medications are indicated to decrease elevated cholesterol.
Statins are considered the best therapy to decrease elevated LDL. If in some cases statins alone cannot decrease the LDL one can use other agents that are available. However, some patients, including young adults, are not able to decrease the low density lipoprotein. These individuals are at greatest risk for cardiovascular disease. Hyperlipidemia is a silent killer.
Studies have proved that high Cholesterol is the risk factor for cardiovascular diseases.
Cholesterol itself is an important factor for proper functioning of our cells. It also helps human body to make hormones and vitamins. The issue arises when …show more content…
As we have learned that nitric oxide helps to keep our vessels dilated and helps to provide more blood to heart.
DMA is an inhibitor of nitric oxide synthesis and high cholesterol stimulates production of
DMA. Cholesterol comes from two sources. One is the food and other is our own body.
Unfortunately, sometimes despite of exercise and healthy dietary habits a person can produce too much cholesterol in liver.
Statins have been in the market for more than 30-40 decades. Despite of the fact they help in the reduction of LDL there are still debates and doubts of their adverse effects. There was a study that was published in American Journal of cardiovascular drugs in 2008. In this study it has been explained how statins work by blocking HMG-CoA reductase in early mevalonate pathway. From Physiology lectures we have learned that mevalonate pathway does not only produce cholesterol.
It helps to generate Coenzyme q10, Heme-A. In addition to cholesterol the other products like sex hormones, Vitamin D,and bile acids are also produced. So blocking the HMG-CoA pathway not only blocked production of cholesterol it also
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