Open Angle Glaucoma Summary

Open-Angle Glaucoma According to the authors Ramdas, Wolfs, Kiefte-de Jong, Hofman, and de Jong (2013) of the article "Nutrient Intake and Risk of Open-Angle Glaucoma: The Rotterdam Study", Open-Angle Glaucoma a is progressive neurodegenerative disease that leads to glaucomatous optic neuropathy and eventually, through glaucomatous visual field loss, to the loss of sight. It is also the most common cause of irreversible blindness worldwide. Increased intraocular pressure, oxidative stress and an impaired ocular blood flow are all contributors to Open-Angle Glaucoma. Their study tested whether the dietary intake of nutrients that either have anti-oxidative properties or influence blood flow is associated with this disease. A total of 3502 people aged 55 years and older participated for which dietary and ophthalmic data at …show more content…
Intraocular pressure was examined at ophthalmic examinations, and dietary intake of nutrients was assessed using questionnaires, which was then adjusted for energy intake. Cox proportional hazard regression analysis was applied to calculate hazard ratios of associations between the baseline intake of nutrients and incident of Open-Angle Glaucoma which adjusted for age, gender, intraocular pressure, intraocular pressure-lowering treatment, and body mass index. During an average follow-up of 9.7 years, 91 participants eventually developed Open-Angle Glaucoma. Overall, this study suggests that people with a high intake of retinol equivalents vitamin A or vitamin B1 have about twofold lower risk of Open-Angle Glaucoma compared to those with a low intake, and people with a high intake of magnesium have about threefold increase in risk of Open-Angle Glaucoma compared to

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