Three consecutive batches of Ibuprofen 400 mg tablet shall be manufactured as per the Batch Manufacturing Record.
Collect samples at different stages of processing as mentioned in the sampling plan for individual process.
Send the samples to Quality Control Laboratory for analysis as per testing plan.
Monitor and record the results of critical control variables and response variables as mentioned in the process parameter table for individual operation.
During the processing of the batches, Current GMP shall be followed.
Compression machine evaluation: Verify the tablets parameters at maximum and minimum speed of machine, then set the parameters for target speed and verify the parameters well within the limits, then check the physical parameters
