Protease Inhibitors Research Paper

Words: 1351
Pages: 6

Juliano, Kyle Lemuel S.
Prof. Louyzza Maria Victoria H. Vasquez
Eng 10
April 26, 2018

What does it take to have a more potent protease inhibitor?

What do think are protease inhibitors? Are they drugs? Well, yes it is. Protease inhibitors are one type of antiretroviral drug which play a great role in the field of science, particularly in biology. These antiretroviral drugs help in reducing the amount of HIV, a virus which copies itself several times as it can by “injecting its genetic material into immune cells in the body called CD4 cells” which serve as the “HIV virus factory”, and bring this amount “to levels that are undetectable” (“HIV: Guide to Protease Inhibitors”). How do these work? They actually block the action
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This world is full mysterious things that scientists still need to study. All the things we see in this world have their own biological components or chemical structure. Water, for instance, is a substance and a liquid that “is composed of two hydrogen atoms and one oxygen atom” which is different from other liquids found on earth (“Water Molecule - Chemical and Physical Properties”). It also has a density greater than oil. Plants have “rigid cell walls” which humans and animals don’t have (“Why animal cells have more variety in shape than plant cells?”). Same goes to drugs. Each drug we find in various drugstores has its own chemical components. Some of them may contain only one type of substance. Some of them may contain combinations of substances. This implies that each thing we see in this world has it’s own level of …show more content…
Combining different protease inhibitors to different antiretrovirals creates various levels of potencies of drugs but how do you determine the most potent? Again one must seek the nature of protease inhibitors’ substance because each of them has complex chemical properties. For a drug to be potent, one must not rely on one factor only. Basing on the nature of drugs for HIV alone could not produce a more potent protease inhibitor. Combining different protease inhibitor to other antiretroviral drugs alone could also not produce a more potent protease inhibitor. And definitely, protein engineeing alone could also not produce a more potent protease inhibitor. So what then does it take to have it? Nature of protease inhibitors may be the most important case to be considered but utilizing the three factors would definitely be able to do the job. And what then could be the more potent drug? In fact, there are lots of more potent drugs that can be produced depending on the type of substance used for the drug and of how this substance is improved either by combining or