Importance Of Medical Genetics And Cytogenetics

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Address Rosebery street, Belfast, BTX XBU

Address Rosebery street, Belfast, BTX XBU

Name
Name

Email shiney.89@gmail.com

Email shiney.89@gmail.com

M.Sc Medical Genetics, University of Y Modules covered: Cytogenetics, biochemical genetics, clinical genetics and molecular genetics including cancer genetics.
Thesis: Restoring the internal countdown in cancer cells: Telomerase and telomere structure based cancer therapies along with further investigation into telomere structure.

B.Sc Biosciences (Honors), X Institute of Higher Learning
4.73/5.00 GPA
Relevant coursework: Cell biology, molecular biology, genetics and evolution, biotechnology and microbiology.
Activities: Member of fine arts self-reliance program and house throw ball team, dance competitions, set designing for drama and theater, fine arts captain. Awards: University fine arts championship.

M.Sc Medical Genetics, University of Y Modules covered: Cytogenetics, biochemical genetics, clinical genetics and molecular genetics including cancer genetics.
Thesis: Restoring the internal countdown in cancer cells: Telomerase and telomere structure based cancer therapies along with further investigation into telomere structure.

B.Sc Biosciences (Honors), X Institute of Higher Learning
4.73/5.00 GPA
Relevant coursework: Cell biology, molecular biology, genetics and evolution, biotechnology and microbiology.
Activities: Member of fine arts self-reliance program and house throw ball team, dance competitions, set designing for drama and theater, fine arts captain. Awards: University fine arts championship.

Oct 2010-Oct
2011, UK

Oct 2010-Oct
2011, UK

Education

Jun 2007-Mar 2010, India

Jun 2007-Mar 2010, India

Research interests
XYZ Institute
Intern – Small molecule inhibitors of PI3K-AKT-mTOR and CDK4/6-pRB inhibitors in spontaneous glioma mouse models and cell lines.
Analysed target inhibiting efficiency and substrate affinity to drug efflux transporters in the brain (P-gp and Bcrp) for CDK4/6 inhibitor PD0332991 and mTOR inhibitor AZD8055 in vitro and in vivo. Identified a PI3K inhibitor under trial in the clinic to cross the blood brain barrier and began a follow-up its pharmacokinetics.
XYZ Institute
Intern – Small molecule inhibitors of PI3K-AKT-mTOR and CDK4/6-pRB inhibitors in spontaneous glioma mouse models and cell lines.
Analysed target inhibiting efficiency and substrate affinity to drug efflux transporters in the brain (P-gp and Bcrp) for CDK4/6 inhibitor PD0332991 and mTOR inhibitor AZD8055 in vitro and in vivo. Identified a PI3K inhibitor under trial in the clinic to cross the blood brain barrier and began a follow-up its pharmacokinetics.
Sep 2012 - Apr 2013, Amsterdam

Sep 2012 - Apr 2013, Amsterdam

Genetics of inherited syndromes, telomeres and telomerase regulation, cytogenetics, genetic and molecular targeting in cancer and natural solutions to ailments.

Research Experience

ABCD
Summer Intern-Plant tissue culture
Completed a diploma in plant tissue culture by mastering various tissue culture techniques, media preparation, bacterial transfection of plant cells and preparation of synthetic seeds within one and a half month.
ABCD
Summer Intern-Plant tissue culture
Completed a diploma in plant tissue culture by mastering various tissue culture techniques, media preparation, bacterial transfection of plant cells and preparation of synthetic seeds within one and a half month.
Apr-May 2008, Bangalore

Apr-May 2008, Bangalore

Health Advisor
Health Store - UK, G2
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