The Kidneys The kidney's day job is removing water waste from your body, but it doubles as a key hormone-producing organ as well. Your kidney is responsible for producing a hormone that stimulates the production of red blood cells, by preventing their premature death. This hormone also helps preserve other cells, like heart and brain cells that have been injured by lack of blood flow. Your kidneys also play a very traceable and key role in regulating blood pressure since they are ideally positioned to measure the pressure of blood pushing into them. If the pressure head is low, like after our ancestors had been bitten by a saber-tooth tiger, they hold onto fluid to maintain our blood pressure. But when they over-react or are misled into thinking we need a higher blood pressure, the kidneys can adjust to high blood pressure. The kidneys are associated with two hormones the erythropoietin and the calcitriol. Erythroproietin promotes the development of red blood cells. Initiate the synthesis of hemoglobin, the molecule within red blood celss that transports oxygen. Erythroproietin is the principal growth factor that promotes the viability, proliferation, and differentiation of mammalian erythroid progenitor cells, functions that are transduced by the specific cell surface.
Calcitriol is a steroid hormone that has long been known for its importants role in regulating body levels of calcium and phosphorus,and in mineralization of a bone. Calcitriol acts on the cells of the intestine to promote the absorption of calcium from food bone to mobilize calcium from the bone to the blood. Calcitriol enters cells and, if they contain receptors for it it binds to them. There are a few pathological conditions of the kidneys. Hyperuricemia is one of them and the common cause of persistent Hyperuricemia is decreasing renal filtration function, which typically occurs in patients who receive long-term diuretic treatment and various types of primary kidney disorders. In human body, the production of uric acid is a complicated process which requires the participation of some enzymes. Those enzymes include two types: one type for promoting the synthesis of uric acid, and the other type for inhibiting formation of uric acids. Human beings have higher levels of uric acid, in part because of a deficiency of the hepatic enzyme, uricase, and Then there is chronic kidney disease which is, also known as chronic renal disease, is a progressive loss in renal function over a period of months or years. The symptoms of worsening kidney function are non-specific,