A. Presence of a single Major Depressive Episode: Five (or more) of the following symptoms have been present during the same two week period and represent a change from previous functioning; at least one the symptoms is either (1) depressed mood, or (2) loss of interest or pleasure. Note: Do not include symptoms that are clearly due to a general medical condition, or mood incongruent delusions or hallucinations.
1) Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g. feels sad or empty) or observation made by others (e.g. appears tearful). Note: In children and adolescents, can e irritable mood. 2) Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation made by others) 3) Significant weight loss when not dieting or weight gain (e.g. a change of more than 5% of body weight in a month), or decrease or increase in