The FDA has not evaluated melatonin supplements for purity, effectiveness, and safety. Due to this there are no regulated manufacturing standards for melatonin. This means that finding other contaminations such has toxic metals or other drugs aren’t likely, but not unheard of. There are three forms of melatonin. They are most commonly found in pill form, but are also available in buccal or sublingual forms that melt and are absorbed into the bloodstream almost instantly. Melatonin supplements have not been extensively studied so there are a lot of unanswered questions with its use, but it is thought to have several helpful uses.
Uses of melatonin supplements include but are not limited to: shift-work disorder, helping blind people establish a sleep-wake cycle, insomnia, reducing the side effects of quitting smoking, Alzheimer’s disease, ringing in the ears(tinnitus), depression, fibromyalgia, irritable bowel syndrome, osteoporosis, migraines, epilepsy, and to subside side effects to chemotherapy. The most common use of melatonin is for insomnia. There are several reasons for insomnia, making it the most widespread problem that can be helped with melatonin supplements. Insomnia due to ADHD, autism, cerebral palsy, and mental retardation in children suggest 5 mg at 8:00 PM daily. Sustained-release and immediate-release supplements have been used. When it is used as a chemotherapy aide it is suggested to take 10-50 mg a day starting seven days before treatment. To aide metastatic cancer is suggested to combine 20 mg of melatonin with 3.75 mg of triptorelin and inject the combination into the muscle every 28 days. It is also believed that by applying melatonin directly